The research groups in the Systems Biology program cover a wide range of topics: from dynamic gene regulatory networks to systems neuroscience, and employ a wide range of model systems to address these issues, including prokaryotes, cell lines, C. elegans, Drosophila and mice.
Underlying this diversity, however, are the common goals of combining systematic and quantitative data collection, using computational models, going beyond molecular descriptions and arriving at a deeper dynamic understanding of complex biological processes.
To achieve these goals the program is strongly interdisciplinary, comprising an increasing number of physicists, mathematicians and computer scientists, in addition to biologists. In this way the program tackles topics such as: signal transduction, gene regulatory networks, multicellular patterning, chemotaxis, systems neuroscience, the evolution of networks, and the impact of stochastic noise at the whole organism level.
We have strong interactions with the local systems biology groups in the UPF. In particular, we consider two labs as being associated to our program:
- The lab of Jordi Garcia-Ojalvo, who focuses on dynamical systems analysis of various biological phenomena.
- The lab of Lucas Carey, who focuses on analysis of single cell behaviour.