CRG
Menu Internet
English SelectedChange language to SpanishChange language to Latin American Spanish
Buscador_Home Buscador_Home
Search
 Bioinformatics and Genomics
Group Leader:



1988 Ph.D. in Statistics. Universitat de Barcelona. (Spain).
1988-1993 Postdoctoral researcher at the Molecular Biology Computer Research Resource. Dana Farber Cancer Institute, Harvard University (Division of Biostatistics) BioMolecular Engineering Research Center. Boston University and Theoretical Biology And Biophysics Group (Los Alamos national Laboratory).
Since 1994 Investigator at Institut Municipal d’Investigació Mèdica (IMIM). Barcelona, (Spain).
Since 2001 Associate Professor at the Universitat Pompeu Fabra and coordinator of the Bioinformatics Programme at the Centre de Regulació Genòmica, Barcelona, (Spain).

Summary

Research in our group focuses on the investigation of the signals involved in gene specification in genomic sequences (promoter elements, splice sites, translation initiation sites, ...). We are interested both in the mechanism of their recognition and processing, and in their evolution. In addition, but related to this basic component of our research, our group is also involved in the development of software for gene prediction and annotation in genomic sequences. Some of our current projects are:

  • Evaluation of Gene Prediction Programmes
  • Gene Prediction software: geneid
  • Genome-Wide Search for Selenoproteins
  • Gene Prediction by Comparative Genomics
  • Splicing
  • Gene Structure Evolution
  • Phylogenetic Reconstruction

See also the Roderic Guigó lab website


Last modification: 09/02/2010


Other Activities
Selected Publications

Buschbeck M, Uribesalgo I, Wibowo I, Rué P, Martin D, Gutierrez A, Morey L, Guigó R, López-Schier H, Di Croce L.
"The histone variant macroH2A is an epigenetic regulator of key developmental genes".
Nat Struct Mol Biol. 16(10):1074-9. Epub 2009 Sep 6. (2009). PubMed ID: 19734898.abstract
Tilgner H, Nikolaou C, Althammer S, Sammeth M, Beato M, Valcárcel J, Guigó R..
Nucleosome positioning as a determinant of exon recognition
Nat Struct Mol Biol 2009 Sep;16(9):996-1001. (2009). PubMed ID: 19684599.abstract
Djebali S, Kapranov P, Foissac S, Lagarde J, Reymond A, Ucla C, Wyss C, Drenkow J, Dumais E, Murray RR, Lin C, Szeto D, Denoeud F, Calvo M, et al.
"Efficient targeted transcript discovery via array-based normalization of RACE libraries"
Nat Methods. 2008 May 25 (AOP) (2008). abstract
Piqué M, López JM, Foissac S, Guigó R and Méndez R.
A Combinatorial Code for CPE-Mediated Translational Control
Cell Vol 132, 434-448 (2008).
The ENCODE Project Consortium (Alioto TS, Estivill X, Foissac S, Guigo R).
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
Nature 447:799-816 (2007). abstract

Other information about the group


Group Members


Bioinformatics and Genomics